Fig. 4

Power for SAFE alternative settings. Statistical power for results with alternative settings alongside default settings for SAFE. The alternative settings tested include 10,000 permutations (‘-10 k’ labels) and bootstrap sampling (‘-boot’ labels). The default setting is with 1000 permutations (‘-1 k’ labels). All power values are shown as a significance value of 0.05. a The KRAS.PROSTATE_UP.V1_DN pathway has been differentially expressed. b The TGF-β SIGNALING pathway has been differentially expressed