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Table 4 Mapping analysis provided by Reactome for the bi53 bicluster obtained with the (212)-simGIC fitness function

From: Pairwise gene GO-based measures for biclustering of high-dimensional expression data

Pathway identifier Pathway name FDR Entities Entities
    found total
R-HSA-3304347 Loss of Function of SMAD4 in Cancer 5.27E-11 2 3
R-HSA-3311021 SMAD4 MH2 Domain Mutants in Cancer 5.27E-11 2 3
R-HSA-3304356 SMAD2/3 Phosphorylation Motif Mutants in Cancer 0.002 2 7
R-HSA-3304349 Loss of Function of SMAD2/3 in Cancer 0.002 2 9
R-HSA-3315487 SMAD2/3 MH2 Domain Mutants in Cancer 0.002 2 9
R-HSA-3656532 TGFBR1 KD Mutants in Cancer 0.002 2 9
R-HSA-3656534 Loss of Function of TGFBR1 in Cancer 0.002 2 9
R-HSA-3304351 Signaling by TGF-beta Receptor Complex in Cancer 0.002 2 10
R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 0.017 2 68
R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 0.017 2 68
R-HSA-2644603 Signaling by NOTCH1 in Cancer 0.017 2 68
  1. Those pathways that includes the word cancer in their names are presented in this table. The complete information about the 133 found pathways can be downloaded as an excel file in the link of Availability of data and materials
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