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Table 2 Comparison of estimated prior probability with true ratio in the simulation study

From: A novel joint analysis framework improves identification of differentially expressed genes in cross disease transcriptomic analysis

DE
status
X
600 700 800 900 1000
Estimate Truth Estimate Truth Estimate Truth Estimate Truth Estimate Truth
(0,0) 0.8857 (0.006)a 0.86 0.8914 (0.006) 0.87 0.8982 (0.006) 0.88 0.9054 (0.005) 0.89 0.9068 (0.003) 0.9
(0,1) 0.041 (0.005) 0.04 0.0356 (0.005) 0.03 0.0284 (0.004) 0.02 0.0218 (0.003) 0.01 0.018 (0.003) 0
(1,0) 0.042 (0.008) 0.04 0.0365 (0.008) 0.03 0.0316 (0.006) 0.02 0.0258 (0.003) 0.01 0.02 (0.004) 0
(1,1) 0.031 (0.003) 0.06 0.0364 (0.002) 0.07 0.0417 (0.004) 0.08 0.0469 (0.005) 0.09 0.0546 (0.004) 0.1
  1. a The values in the parentheses represent the standard deviation summarized from 10 repeated runs