Fig. 3

Comparison of different gene prioritization approaches offered in Arete app. a Box plot of ROC AUC scores of leave-one-out, 3-fold and 5-fold cross-validation for 69 different sets of disease-related genes. b Percentages of genes associated with multiple diseases in our reference set. Bottom row shows corresponding fold-enrichment statistics for the four quartiles of ranked gene lists profiled using 3-fold (c), 5-fold d and leave-one-out e cross-validation schemes