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Table 1 Averaged data for Passing Bablok analysis and Spearman correlation for mass spectra of the same biosamples after normalization according to the SantaOmics algorithm

From: Label-free data standardization for clinical metabolomics

 

maXis

Apex Ultra

OrbiTrap Elite

micrOTOF-Q

IFunnel Q-ToF

maXis

 

0.46 ± 0.08

0.56 ± 0.09

0.70 ± 0.07

0.73 ± 0.04

Apex Ultra

1.01 ± 0.14

0.01 ± 0.01

–

0.68 ± 0.07

0.50 ± 0.07

0.27 ± 0.06

OrbiTrap Elite

1.10 ± 0.22

0.05 ± 0.06

1.12 ± 0.22

0.021 ± 0.04

–

0.58 ± 0.12

0.34 ± 0.10

micrOTOF-Q

0.88 ± 0.16

−0.15 ± 0.09

0.91 ± 0.31

−0.19 ± 0.16

0.84 ± 0.13

−0.19 ± 0.06

–

0.67 ± 0.10

IFunnel Q-ToF

0.99 ± 0.22

0.05 ± 0.03

0.98 ± 0.30

0.03 ± 0.05

0.96 ± 0.39

0.00 ± 0.05

1.09 ± 0.24

0.25 ± 0.03

–

  1. All data are presented as the mean ± standard deviation for three independent experiments (i.e., for samples from three volunteers). Individual data points are presented in Additional file 3: Tables S2-S10. The slopes and intercepts (just below the slope values) for Passing Bablok analysis are presented in the lower left part of the table. The Spearman correlation values are presented in the upper right part of the table