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Table 1 Comparison of classification performance with three types of markers in the breast cancer dataset

From: Mining pathway associations for disease-related pathway activity analysis based on gene expression and methylation data

Classifiers

Markers

Sensitivity

Specificity

Accuracy

kNN

genes

93.6 (2.06)

82.56 (3.29)

88.08 (1.94)

pathways

92.44 (1.08)

89.53 (1.76)

90.99 (1.2)

pathway-sets

97.09 (2.06)

90.7 (1.24)

93.9 (1.03)

RF

genes

87.21 (1.76)

87.79 (1.08)

87.5 (0.82)

pathways

93.31 (2.62)

92.73 (1.49)

93.02 (1.08)

pathway-sets

93.31 (2.62)

92.73 (1.49)

93.31 (1.03)

SVM

genes

86.63 (1.08)

86.63 (2.41)

86.63 (1.52)

pathways

93.9 (1.73)

91.28 (1.08)

92.59 (1.23)

pathway-sets

91.57 (3.27)

92.44 (1.08)

92.01 (1.91)

Naïve Bayes

genes

86.63 (1.08)

86.63 (2.41)

86.63 (1.52)

pathways

93.9 (1.73)

91.28 (1.08)

92.59 (1.23)

pathway-sets

91.57 (3.27)

92.44 (1.08)

92.01 (1.91)