Fig. 8
From: A biologically informed method for detecting rare variant associations
Wilcoxon power analysis. Statistical power estimates for multiple weighting methods assessed at varying odds ratios using the Wilcoxon rank sum test. Results are based on 25 kb bins containing 50 (±10) variants with 10 of these representing causal variants. The different colors represent the various weighting schemes analyzed in BioBin. Control only weighting is presented with a dashed line to draw attention to the inflated type I error (presented in Fig. 5 and Additional file 2: Figure S1) of this weighting method