Fig. 7
From: A biologically informed method for detecting rare variant associations
Logistic regression power analysis. Statistical power estimates for multiple weighting methods assessed at varying odds ratios using logistic regression analysis. Results are based on 25 kb bins containing 50 (±10) variants with 10 of these representing causal variants. The different colors represent the various weighting schemes in BioBin that were analyzed. Control only weighting is presented with a dashed line to draw attention to the inflated type I error (presented in Fig. 6 and Additional files 2: Figure S1 and Additional file 3: Figure S2) of this weighting method