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Fig. 8 | BioData Mining

Fig. 8

From: Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer

Fig. 8

Clustered heatmap of the K1/k2 signature identified by JAMMIT in 50 liver tissue samples. The heatmap for the K1/k2 signature, \( {\omega}_{mRNA}^{\left({K}_1/{k}_2\right)} \), exhibits very uniform expression on the normals (columsn 1–20) and very high variability on the tumor samples. On the tumor samples, we note significant down-regulation of \( {\omega}_{mRNA}^{\left({K}_1/{k}_2\right)} \) expression patterns on a subset of seven (7) HCC, six (6) ICC and 2 sarcomas. The remaining 15 HCC had \( {\omega}_{mRNA}^{\left({K}_1/{k}_2\right)} \) expression profiles very similar to the 20 normal samples

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