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Fig. 7 | BioData Mining

Fig. 7

From: Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer

Fig. 7

A 12-gene mRNA signature for ovarian cancer anchored upstream by IL4 predicts overall survival. a KM plots of patients in discovery data set with prognostic scores based on the 12-gene mRNA signature φ (12)IL4 in the top (red) and bottom (blue) quartiles. Note the two groups of 72 patients each (144 total) show significant differences in survival based on the separation between their respective KM plots. b KM plots of patients in test data set with φ (12)IL4 prognostic scores in the top (red) and bottom (blue) quartiles. The two groups of 24 patients each (48 total) show significant differences in survival based on the separation between their respective KM plots. Note the prognostic scores for the test patients were computed by projecting the test data matrix for φ (12)IL4 onto the ESM derived from discovery data matrix for φ (12)IL4

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BioData Mining

ISSN: 1756-0381