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Fig. 5 | BioData Mining

Fig. 5

From: Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer

Fig. 5

40-gene signature φ (40)IL4 for ovarian cancer anchored upstream by IL4 is robustly associated with survival. a Clustered heatmap of the mRNA signature φ (40)IL4 realized in the 291-sample training data set. b KM plots of patients in training data set with prognostic scores in the top and bottom quartiles based on the eigen-survival model based on the realization of φ (40)IL4 in 291-sample discovery data set. c Clustered heatmap of φ (40)IL4 realized in the 99-sample test data set. d KM plots of patients in unseen test data set with prognostic scores in the top and bottom quartiles. The prognostic scores for the test patients were obtained by projecting the realization of φ (40)IL4 in the test data onto the eigen-survival model for φ (40)IL4 derived from the discovery data set (green arrows)

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