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Table 7 Pathway analysis of the 150 extracted NBG

From: Building a glaucoma interaction network using a text mining approach

Pathway name Count of genes in pathway FDR % of genes in pathway Supporting References
Gonadotropin releasing hormone receptor pathwayb 9   8.1 [58]
Interleukin signaling pathwayb 6   5.4 [69]
Wnt signalling pathwaya 5 0.006 4.2 [56, 57]
Jak-STAT signaling pathwaya 5 0.001 1.8 [70]
PDGF signaling pathwayb 5   4.5 [71]
TGF-beta signaling pathwaya 4 0.01 3.6 [72]
Apoptosis signaling pathway b 2   1.8 [73, 74]
  1. Common pathways, reported by both GeneCodis and PANTHER, are suffixed by a and the associated false discovery rate (FDR) from GeneCodis is reported. Pathways, reported by PANTHER, are suffixed by b. The percentage of total genes in the pathway is reported along supporting references that link glaucoma to the pathway