Building a glaucoma interaction network using a text mining approach

Table 1 Glaucoma benchmark and non-benchmark genes used in building the network

Abbreviation	Definition	Number	Percent
BO	Benchmark glaucoma genes from OMIM database queried with “Glaucoma”	155	51 %
BD	Benchmark glaucoma genes from DisGeNET database queried with “Glaucoma”	180	59 %
BC	Benchmark glaucoma genes from the intersection of OMIM and DisGeNET databases	30 (BO∩BD)	10 %
BG	Benchmark glaucoma genes from union of BO and BD	305 (BO⋃BD)	100 %
NBG	Non-benchmark genes from PubMed Central	150	N/A

For simplicity, benchmark genes used to build the interaction network are abbreviated as BG. If BG are obtained from OMIM, then we call them BO. If BG are obtained from DisGeNET, then we call them BD. Benchmark genes, common to OMIM and DisGeNET, are called BC. Genes that are not benchmark genes are called NBG. The definition, number and percentages of all benchmark genes are listed in columns 2 to 4

ISSN: 1756-0381