Fig. 4From: Evolutionary triangulation: informing genetic association studies with evolutionary evidencePercentage of ET SNPs within ± 100 Kb of the LCT-MCM genic region. In all two-way comparisons, only a small proportion (<0.2 %) of the SNPs are within ± 100 Kb of the LCT-MCM region. For example, the 95th percentile FST threshold of two way comparison between CEU and TSI (red line) generates 68,106 SNPs, only 91 (0.133 %) of which locate within ± 100 Kb of the LCT-MCM region. In contrast, signals from the three way comparison of FST (ET) more than 60 % of the ET SNPs are within the same region (blue line). The black line represents the pairwise comparisons between CEU and CHB, while the green line represents between CHB and TSIBack to article page