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Fig. 4 | BioData Mining

Fig. 4

From: Evolutionary triangulation: informing genetic association studies with evolutionary evidence

Fig. 4

Percentage of ET SNPs within ± 100 Kb of the LCT-MCM genic region. In all two-way comparisons, only a small proportion (<0.2 %) of the SNPs are within ± 100 Kb of the LCT-MCM region. For example, the 95th percentile FST threshold of two way comparison between CEU and TSI (red line) generates 68,106 SNPs, only 91 (0.133 %) of which locate within ± 100 Kb of the LCT-MCM region. In contrast, signals from the three way comparison of FST (ET) more than 60 % of the ET SNPs are within the same region (blue line). The black line represents the pairwise comparisons between CEU and CHB, while the green line represents between CHB and TSI

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