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Fig. 2 | BioData Mining

Fig. 2

From: Evolutionary triangulation: informing genetic association studies with evolutionary evidence

Fig. 2

FST distributions among ET comparisons of CEU, GIH and YRI populations. Shows the FST distributions of CEU-GIH, CEU-YRI and GIH-YRI. Similar in the three distributions, most FST’s are less than 0.1, which means that most SNPs are not differentiated greatly among population. The red dotted lines indicates the percentile thresholds we use to generate ET SNPs. For example, for CEU-GIH and CEU-YRI we took SNPs having an FST greater than or equal to 95th percentile, which are those to right of the red dotted lines. And for GIH-YRI, we took SNPs having an FST less than or equal to than 5th percentile, which are those to left of the red dotted line. By overlapping these three sets of SNPs, we could generate the ET SNPs

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