TY - JOUR AU - Evans, R. G. AU - Naidu, B. AU - Rajpoot, N. M. AU - Epstein, D. AU - Khan, M. PY - 2012 DA - 2012// TI - Toponome imaging system: multiplex biomarkers in oncology JO - Trends Mol Med VL - 18 UR - https://doi.org/10.1016/j.molmed.2012.10.003 DO - 10.1016/j.molmed.2012.10.003 ID - Evans2012 ER - TY - JOUR AU - Schubert, W. AU - Bonnekoh, B. AU - Pommer, A. J. AU - Philipsen, L. AU - Böckelmann, R. AU - Malykh, Y. PY - 2006 DA - 2006// TI - Analyzing proteome topology and function by automated multidimensional fluorescence microscopy JO - Nat Biotechnol VL - 24 UR - https://doi.org/10.1038/nbt1250 DO - 10.1038/nbt1250 ID - Schubert2006 ER - TY - JOUR AU - Gerdes, M. J. AU - Sevinsky, C. J. AU - Sood, A. AU - Adak, S. AU - Bello, M. O. AU - Bordwell, A. PY - 2013 DA - 2013// TI - Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue JO - Proc Natl Acad Sci VL - 110 UR - https://doi.org/10.1073/pnas.1300136110 DO - 10.1073/pnas.1300136110 ID - Gerdes2013 ER - TY - JOUR AU - Clarke, G. M. AU - Zubovits, J. T. AU - Shaikh, K. a. AU - Wang, D. AU - Dinn, S. R. AU - Corwin, A. D. PY - 2013 DA - 2013// TI - A novel, automated technology for multiplex biomarker imaging and application to breast cancer JO - Histopathology VL - 64 UR - https://doi.org/10.1111/his.12240 DO - 10.1111/his.12240 ID - Clarke2013 ER - TY - JOUR AU - Stoeckli, M. AU - Chaurand, P. AU - Hallahan, D. E. AU - Caprioli, R. M. PY - 2001 DA - 2001// TI - Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues JO - Nat Med VL - 7 UR - https://doi.org/10.1038/86573 DO - 10.1038/86573 ID - Stoeckli2001 ER - TY - JOUR AU - Giesen, C. AU - Wang, H. a. O. AU - Schapiro, D. AU - Zivanovic, N. AU - Jacobs, A. AU - Hattendorf, B. PY - 2014 DA - 2014// TI - Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry JO - Nat Methods VL - 11 UR - https://doi.org/10.1038/nmeth.2869 DO - 10.1038/nmeth.2869 ID - Giesen2014 ER - TY - JOUR AU - Bandura, D. R. AU - Baranov, V. I. AU - Ornatsky, O. I. AU - Antonov, A. AU - Kinach, R. AU - Lou, X. PY - 2009 DA - 2009// TI - Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry JO - Anal Chem VL - 81 UR - https://doi.org/10.1021/ac901049w DO - 10.1021/ac901049w ID - Bandura2009 ER - TY - JOUR AU - Van Manen, H. J. AU - Kraan, Y. M. AU - Roos, D. AU - Otto, C. PY - 2005 DA - 2005// TI - Single-cell Raman and fluorescence microscopy reveal the association of lipid bodies with phagosomes in leukocytes JO - Proc Natl Acad Sci of the U S A VL - 102 UR - https://doi.org/10.1073/pnas.0502746102 DO - 10.1073/pnas.0502746102 ID - Van Manen2005 ER - TY - STD TI - Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, et al.Multiplexed ion beam imaging of human breast tumors. Nat Med. 2014; 20. ID - ref9 ER - TY - JOUR AU - Goodwin, R. J. a. PY - 2012 DA - 2012// TI - Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences JO - J Proteome VL - 75 UR - https://doi.org/10.1016/j.jprot.2012.04.012 DO - 10.1016/j.jprot.2012.04.012 ID - Goodwin2012 ER - TY - JOUR AU - Schubert, W. AU - Gieseler, A. AU - Krusche, A. AU - Serocka, P. AU - Hillert, R. PY - 2012 DA - 2012// TI - Next-generation biomarkers based on 100-parameter functional super-resolution microscopy TIS JO - New Biotechnol VL - 29 UR - https://doi.org/10.1016/j.nbt.2011.12.004 DO - 10.1016/j.nbt.2011.12.004 ID - Schubert2012 ER - TY - JOUR AU - Bode, M. AU - Krusche, A. PY - 2007 DA - 2007// TI - Toponome Imaging System (TIS): imaging the proteome with functional resolution JO - Nat Methods Appl Notes VL - 4 UR - https://doi.org/10.1038/nmeth0107-1 DO - 10.1038/nmeth0107-1 ID - Bode2007 ER - TY - JOUR AU - Friedenberger, M. AU - Bode, M. AU - Krusche, A. AU - Schubert, W. PY - 2007 DA - 2007// TI - Fluorescence detection of protein clusters in individual cells and tissue sections by using toponome imaging system: sample preparation and measuring procedures JO - Nat Protoc VL - 2 UR - https://doi.org/10.1038/nprot.2007.320 DO - 10.1038/nprot.2007.320 ID - Friedenberger2007 ER - TY - JOUR AU - Raza, S. E. A. AU - Humayun, A. AU - Abouna, S. AU - Nattkemper, T. W. AU - Epstein, D. B. A. AU - Khan, M. PY - 2012 DA - 2012// TI - RAMTaB: robust alignment of multi-tag bioimages JO - PLoS ONE VL - 7 UR - https://doi.org/10.1371/journal.pone.0030894 DO - 10.1371/journal.pone.0030894 ID - Raza2012 ER - TY - JOUR AU - Nattkemper, T. W. AU - Ritter, H. J. AU - Schubert, W. PY - 2001 DA - 2001// TI - A neural classifier enabling high-throughput topological analysis of lymphocytes in tissue sections JO - Inf Technol Biomed IEEE Trans VL - 5 UR - https://doi.org/10.1109/4233.924804 DO - 10.1109/4233.924804 ID - Nattkemper2001 ER - TY - JOUR AU - Nattkemper, T. W. AU - Wersing, H. AU - Schubert, W. AU - Ritter, H. PY - 2002 DA - 2002// TI - A neural network architecture for automatic segmentation of fluorescence micrographs JO - Neurocomputing VL - 48 UR - https://doi.org/10.1016/S0925-2312(01)00642-7 DO - 10.1016/S0925-2312(01)00642-7 ID - Nattkemper2002 ER - TY - JOUR AU - Schubert, W. AU - Friedenberger, M. AU - Haars, R. AU - Bode, M. AU - Philipsen, L. AU - Nattkemper, T. PY - 2002 DA - 2002// TI - Automatic recognition of muscle-invasive t-lymphocytes expressing Dipeptidyl-Peptidase IV (CD26) and analysis of the associated cell surface phenotypes JO - J Theoretical Med VL - 4 UR - https://doi.org/10.1080/10273660290015189 DO - 10.1080/10273660290015189 ID - Schubert2002 ER - TY - JOUR AU - Herold, J. AU - Schubert, W. AU - Nattkemper, T. W. PY - 2010 DA - 2010// TI - Automated detection and quantification of fluorescently labeled synapses in murine brain tissue sections for high throughput applications JO - J Biotechnol VL - 149 UR - https://doi.org/10.1016/j.jbiotec.2010.03.004 DO - 10.1016/j.jbiotec.2010.03.004 ID - Herold2010 ER - TY - JOUR AU - Khan, A. M. AU - Raza, S. E. A. AU - Khanm, M. AU - Rajpoot, N. M. PY - 2014 DA - 2014// TI - Cell phenotyping in multi-tag fluorescent bioimages JO - Neurocomputing VL - 134 UR - https://doi.org/10.1016/j.neucom.2013.08.043 DO - 10.1016/j.neucom.2013.08.043 ID - Khan2014 ER - TY - JOUR AU - Loyek, C. AU - Rajpoot, N. M. AU - Khan, M. AU - Nattkemper, T. W. PY - 2011 DA - 2011// TI - BioIMAX: A Web 2.0 approach for easy exploratory and collaborative access to multivariate bioimage data JO - BMC Bioinformatics VL - 12 UR - https://doi.org/10.1186/1471-2105-12-297 DO - 10.1186/1471-2105-12-297 ID - Loyek2011 ER - TY - JOUR AU - Kölling, J. AU - Langenkämper, D. AU - Abouna, S. AU - Khan, M. AU - Nattkemper, T. W. PY - 2012 DA - 2012// TI - WHIDE–a web tool for visual data mining colocation patterns in multivariate bioimages JO - Bioinformatics (Oxford, England) VL - 28 UR - https://doi.org/10.1093/bioinformatics/bts104 DO - 10.1093/bioinformatics/bts104 ID - Kölling2012 ER - TY - JOUR AU - Kovacheva, V. N. AU - Khan, A. M. AU - Khan, M. AU - Epstein, D. AU - Rajpoot, N. M. PY - 2014 DA - 2014// TI - DiSWOP: a novel measure for cell-level protein network analysis in localised proteomics image data JO - Bioinformatics VL - 30 UR - https://doi.org/10.1093/bioinformatics/btt676 DO - 10.1093/bioinformatics/btt676 ID - Kovacheva2014 ER - TY - JOUR AU - Linke, B. AU - Pierre, S. AU - Coste, O. AU - Angioni, C. AU - Becker, W. AU - Maier, T. J. PY - 2009 DA - 2009// TI - Toponomics analysis of drug-induced changes in arachidonic acid-dependent signaling pathways during spinal nociceptive processing JO - J Proteome Res VL - 8 UR - https://doi.org/10.1021/pr900106v DO - 10.1021/pr900106v ID - Linke2009 ER - TY - JOUR AU - Fonville, J. M. AU - Carter, C. AU - Cloarec, O. AU - Nicholson, J. K. AU - Lindon, J. C. AU - Bunch, J. PY - 2012 DA - 2012// TI - Robust data processing and normalization strategy for MALDI mass spectrometric imaging JO - Anal Chem VL - 84 UR - https://doi.org/10.1021/ac201767g DO - 10.1021/ac201767g ID - Fonville2012 ER - TY - JOUR AU - Schüffler, P. J. AU - Schapiro, D. AU - Giesen, C. AU - Wang, H. a. O. AU - Bodenmiller, B. AU - Buhmann, J. M. PY - 2015 DA - 2015// TI - Automatic single cell segmentation on highly multiplexed tissue images JO - Cytometry Part A VL - 87 UR - https://doi.org/10.1002/cyto.a.22702 DO - 10.1002/cyto.a.22702 ID - Schüffler2015 ER - TY - JOUR AU - Bhattacharya, S. AU - Mathew, G. AU - Ruban, E. AU - Epstein, D. B. A. AU - Krusche, A. AU - Hillert, R. PY - 2010 DA - 2010// TI - Toponome Imaging System : in situ protein network mapping in normal and cancerous Colon from the same patient reveals more than five-thousand cancer specific protein clusters and their subcellular annotation by using a three symbol code research articles JO - J Proteome Res VL - 9 UR - https://doi.org/10.1021/pr100157p DO - 10.1021/pr100157p ID - Bhattacharya2010 ER - TY - CHAP AU - Tomasi, C. AU - Manduchi, R. PY - 1998 DA - 1998// TI - Bilateral filtering for gray and color images BT - Sixth International Conference on Computer Vision (IEEE Cat. No.98CH36271) PB - IEEE CY - Bombay ID - Tomasi1998 ER - TY - BOOK AU - González, R. C. AU - Woods, R. E. PY - 2008 DA - 2008// TI - Digital image processing PB - Pearson/Prentice Hall CY - USA ID - González2008 ER - TY - CHAP AU - Bishop, C. M. ED - Jordan, M. ED - Kleinberg, J. ED - Schölkopf, B. PY - 2006 DA - 2006// TI - Pattern. Pattern Recognition and Machine Learning BT - Information Science and Statistics PB - Springer CY - Berlin Heidelberg ID - Bishop2006 ER - TY - JOUR AU - Herold, J. AU - Loyek, C. AU - Nattkemper, T. W. PY - 2011 DA - 2011// TI - Multivariate image mining JO - Wiley Interdiscip Rev Data Mining Knowl Discov VL - 1 UR - https://doi.org/10.1002/widm.4 DO - 10.1002/widm.4 ID - Herold2011 ER - TY - BOOK AU - Bigi, B. PY - 2003 DA - 2003// TI - Using Kullback-Leibler distance for text categorization. vol. 2633 of Lecture Notes in Computer Science PB - Springer CY - Berlin Heidelberg ID - Bigi2003 ER -