Table 2 Shown are the five SNP-SNP interactions with the highest information gain values for BMI within the Statistical Epistasis Network at the percolation threshold

From: Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity

Interaction	SNP1	Gene1	SNP2	Gene2	Information Gain	Permuted P-value
rs2867133,rs9878325	rs2867133	TMEM18	rs9878325	ETV5	0.0473789	<0.001
rs7110708,rs8105874	rs7110708	BDNF	rs8105874	KCTD15	0.043324175	<0.001
rs17360705,rs1673518	rs17360705	SEC16B	rs1673518	MC4R	0.042418682	<0.001
rs10798574,rs2245826	rs10798574	SEC16B	rs2245826	BDNF	0.03917757	<0.001
rs8179316,rs1316803	rs8179316	NEGR1	rs1316803	TMEM18	0.038534544	<0.001

The corresponding gene for each SNP is also shown. SNP-SNP interactions are measured using information gain [IG(A;B;C)]. P-values were calculated from a 1000 permutations

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ISSN: 1756-0381

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