Skip to main content
Fig. 2 | BioData Mining

Fig. 2

From: A significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis

Fig. 2

Results of the genome-wide CNV-weighted linkage analyses. The plots illustrate genome-wide CNV-weighted linkage scores of the parametric (dominant and recessive) and non-parametric (NPLALL statistics) models under the three affection status models (ASM1-3). The sum of average family-wise linkage scores LOD scores for parametric and Z scores for non-parametric models were calculated over regions with the presence of copy number variation that is shared between at least two individuals within and across families. The thresholds for significance (dotted lines) were defined after a 1000-fold simulation analysis including FWER correction

Back to article page