Skip to main content
Fig. 3 | BioData Mining

Fig. 3

From: Genome-wide predictors of NF-κB recruitment and transcriptional activity

Fig. 3

Role of pre-bound transcription factors in p65 recruitment. a Probability of p65 recruitment plotted as a function of the number of transcription factors (TFs) pre-bound at regulatory sites (occupancy). CTCF and RAD21 (cohesin) do not contribute to the occupancy count. b Enrichment of p65 binding events at two classes of regulatory sites. TSS-distal stage 1 sites have a single TF pre-bound. TSS-distal stage 2 sites have TF occupancy from 2 to 4. Log-odds of p65 recruitment reported for each protein with all stage 1 and stage 2 sites as background, respectively. Significance estimated by the Fisher’s exact test. TFs are ordered based on log-odds at stage 1 TSS-distal sites

Back to article page
\