From: Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry
Outcome (n) | % or mean (± SD) | OR or β (95 % CI or SE) | P-value |
---|---|---|---|
Hypertension, baseline (n = 6,422) | 56 % | 1.20 (0.90 – 1.59) | 0.21 |
Hypertension, lifetime (n = 8,691) | 78 % | 1.23 (0.82 – 1.86) | 0.32 |
Type 2 diabetes (n = 1,356) | 12 % | 1.32 (0.91 – 1.91) | 0.15 |
Albumin (g/dL), serum (n = 8,094) | 4.05 (0.51) | −0.001 (0.04) | 0.88 |
Albumin creatinine ratio (mg/mmol) (n = 1,210) | 14.0 (861.10) | −123.82 (176.60) | 0.48 |
Albumin (mg/dL), urinary (n = 1,199) | 16.7 (640.2) | −36.35(131.80) | 0.78 |
Blood urea nitrogen (mg/dL) (n = 10,111) | 11.00 (13.55) | −0.23 (0.93) | 0.80 |
Body mass index (kg/m2) (n = 9,247) | 27.25 (7.21) | 0.74 (0.51) | 0.15 |
Creatinine (mg/dL), serum (n = 10,288) | 0.88 (1.99) | 0.07 (0.13) | 0.59 |
Creatinine (g/kg/day), urinary (n = 172) | 70.00 (73.89) | 23.05 (38.86) | 0.55 |
Diastolic blood pressure (mm Hg), baseline (n = 10,025) | 76.00 (15.68) | 0.48 (1.07) | 0.66 |
Diastolic blood pressure (mm Hg), post-medication (n = 5,653) | 79.00 (10.06) | 0.29 (0.90) | 0.75 |
Diastolic blood pressure (mm Hg), pre-medication (n = 7,009) | 75.00 (11.28) | 0.38 (0.92) | 0.68 |
Glucose (mg/dL) (n = 9,918) | 96.00 (34.33) | 0.04 (2.37) | 0.99 |
Glycated hemoglobin (mg/dL) (n = 2,925) | 6.30 (1.80) | 0.07 (0.23) | 0.75 |
HDL-C (mg/dL) (n = 5,096) | 50.00 (16.99) | −1.02 (1.65) | 0.54 |
HDL-c (mg/dL) post-medication (n = 2,097) | 47.75 (16.56) | −2.95 (2.48) | 0.23 |
HDL-C (mg/dL), pre-medication (n = 4,273) | 51.00 (17.09) | −0.91 (1.81) | 0.61 |
Heart rate (beats per minute) (n = 783) | 76.00 (11.14) | −3.28 (2.67) | 0.22 |
Insulin (IU/mL) (n = 343) | 16.90 (74.36) | −11.15 (24.38) | 0.65 |
LDL-C (mg/dL), regardless of medication status | 99.00 (35.18) | −1.17 (3.42) | 0.73 |
LDL-C (mg/dL), post-medication | 96.00 (38.90) | 4.95 (5.78) | 0.39 |
LDL-C (mg/dL), pre-medication | 105.00 (39.70) | −3.20 (4.26) | 0.45 |
PR Interval (msec) (n = 781) | 159.00 (17.92) | −0.12 (4.30) | 0.98 |
QRS duration (msec) (n = 837) | 82.00 (8.65) | 7.98 (1.99) | 6.7x10 -5 |
QT interval (msec) (n = 783) | 376.00 (27.84) | 11.62 (6.66) | 0.08 |
Systolic blood pressure (mm Hg), baseline (n = 10,025) | 125.00 (22.54) | −1.43 (1.54) | 0.35 |
Systolic blood pressure (mm Hg), post-medication (n = 5,653) | 132.00 (16.03) | 0.78 (1.43) | 0.58 |
Systolic blood pressure (mm Hg), pre-medication (n = 7,009) | 123.00 (16.38) | −0.0003 (1.34) | 0.99 |
Total cholesterol (mg/dL), regardless of medication status (n = 5,439) | 175.00 (39.48) | −1.65 (3.70) | 0.65 |
Total cholesterol (mg/dL), post-medication (n = 2,150) | 173.50 (44.22) | 3.48 (6.58) | 0.60 |
Total cholesterol (mg/dL), pre-medication (n = 4,642) | 181.00 (44.86) | −3.57 (4.55) | 0.43 |
Triglycerides (mg/dL), regardless of medication status (n = 5,269) | 98.00 (69.46) | 3.34 (6.61) | 0.61 |
Triglycerides (mg/dL), post-medication (n = 2,115) | 110.00 (74.07) | 10.63 (11.07) | 0.34 |
Triglycerides (mg/dL), pre-medication (n = 4,445) | 97.00 (79.25) | 2.00 (8.20) | 0.81 |
Uric acid (mg/dL) (n = 2,465) | 5.40 (2.18) | 0.06 (0.29) | 0.84 |