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Table 5 Top regulators for eQTL-hotspot gene groups predicted by the SPF method in gWormNet

From: On predicting regulatory genes by analysis of functional networks in C. elegans

EQTL-hotspot

Chromosome

Gene

Function

 

Juvenile worms

 

1

I

pop-1

TCF/LEF TF, WNT pathway

 

1

I

xnp-1

DNA helicase, stress response

 

1

I

lin-17

Wnt signaling

 

1

I

lin-44

Wnt signaling

 

Old worms

 

5

II

age-1

PI3K, daf-2 Insulin pathway

 
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BioData Mining

ISSN: 1756-0381