Table 1 Previously identified LOAD SNPs
From: Identifying genetic interactions associated with late-onset Alzheimer’s disease
# | Gene | AlzGene SNP | Odds ratio (95% CI) | p value | ADRC SNP | r2 | TGen SNP | r2 |
|---|---|---|---|---|---|---|---|---|
1 | APOE 4 | rs429358 | 3.685 (3.30-4.12) | <1E-50 | Same | - | Same | - |
2 | CR1 | rs3818361 | 1.174 (1.14-1.21) | 4.72E-21 | Same | - | rs6656401 | 0.840 |
3 | PICALM | rs3851179 | 0.879 (0.86-0.9) | 2.85E-20 | Same | - | rs7110631 | 0.841 |
4 | MS4A6A | rs610932 | 0.904 (0.88-0.93) | 1.81E-11 | Same | - | rs574695 | 0.935 |
5 | CD33 | rs3865444 | 0.893 (0.86-0.93) | 2.04E-10 | Same | - | Same | - |
6 | MS4A4E | rs670139 | 1.079 (1.05-1.11) | 9.51E-10 | rs600550 | 1 | rs676309 | 1 |
7 | CD2AP | rs9349407 | 1.117 (1.08-1.16) | 2.75E-09 | rs9296559 | 1 | rs9296558 | 1 |
8 | GAB2 | rs2373115 | 0.85 (0.76-0.94) | Same | - | Same | - | |
9 | SORL1 | rs2282649 | 1.10 (1.03-1.17) | rs726601 | 0.922 | rs726601 | 0.922 | |
10 | TF | rs1049296 | 1.18 (1.06-1.31) | Same | - | Same | - |