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Table 1 Previously identified LOAD SNPs

From: Identifying genetic interactions associated with late-onset Alzheimer’s disease

# Gene AlzGene SNP Odds ratio (95% CI) p value ADRC SNP r2 TGen SNP r2
1 APOE 4 rs429358 3.685 (3.30-4.12) <1E-50 Same - Same -
2 CR1 rs3818361 1.174 (1.14-1.21) 4.72E-21 Same - rs6656401 0.840
3 PICALM rs3851179 0.879 (0.86-0.9) 2.85E-20 Same - rs7110631 0.841
4 MS4A6A rs610932 0.904 (0.88-0.93) 1.81E-11 Same - rs574695 0.935
5 CD33 rs3865444 0.893 (0.86-0.93) 2.04E-10 Same - Same -
6 MS4A4E rs670139 1.079 (1.05-1.11) 9.51E-10 rs600550 1 rs676309 1
7 CD2AP rs9349407 1.117 (1.08-1.16) 2.75E-09 rs9296559 1 rs9296558 1
8 GAB2 rs2373115 0.85 (0.76-0.94)   Same - Same -
9 SORL1 rs2282649 1.10 (1.03-1.17)   rs726601 0.922 rs726601 0.922
10 TF rs1049296 1.18 (1.06-1.31)   Same - Same -
  1. AlzGene SNP: the SNP in the AlzGene meta-analysis, along with the relevant odds ratios and p values (the latter for those SNPs with p values <0.00001); ADRC SNP: the corresponding SNP in the ADRC dataset, along with the r2 scores; TGen SNP: the corresponding SNP in the TGen dataset, along with the r2 scores for linkage disequilibrium.
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