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Table 1 Top genes with highest FC change between the average gene expression values between the gained and normal and lost and normal samples

From: Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells

HGNC Gene Gene description Logarithmic fold change Number Adjusted p-value
GSTT1 ENSG00000184674 Glutathione S-transferase theta-1 1.8701 1 <0.0139
KCNMA1 ENSG00000156113 Calcium-activated potassium channel 1.7972 1 <0.0139
RNFT1 ENSG00000189050 RING finger and transmembrane 1.0443 1 <0.0139
APPBP2 ENSG00000062725 Amyloid protein-binding protein 0.9715 1 <0.0139
SMCHD1 ENSG00000101596 Structural maintenance of chromosomes exible hinge domain-containing protein 1 0.85418 1 <0.0139
NDC80 ENSG00000080986 Kinetochore protein NDC80 homolog 0.80433 1 <0.0139
HEATR6 ENSG00000068097 HEAT repeat-containing protein 0.77267 1 <0.0139
HLA-DRB5 ENSG00000198502 HLA class II histocompatibility antigen, DRB5 beta chain precursor 0.72371 5 <0.0139
METTL4 ENSG00000101574 Methyltransferase-like protein 0.70292 1 <0.0139
PPM1D ENSG00000170836 Protein phosphatase 1D 0.6493 1 <0.0139
PDPN ENSG00000162493 Podoplanin precursor (Glycoprotein 36) -2.9885 1 <0.036
ALPL ENSG00000162551 Alkaline phosphatase, tissue nonspecific isozyme precursor -2.16 1 <0.036
NPPB ENSG00000120937 Natriuretic peptides B precursor -1.6065 1 <0.036
RCAN3 ENSG00000117602 Calcipressin-3 (Regulator of calcineurin 3) -1.2506 1 <0.036
DFFA ENSG00000160049 DNA fragmentation factor subunit alpha -1.1259 1 <0.036
TPRG1L ENSG00000158109 Tumor protein p63-regulated gene 1-like protein -1.1232 1 <0.036
CDA ENSG00000158825 Cytidine deaminase -1.0503 1 <0.036
DDI2 ENSG00000197312 Protein DDI1 homolog 2 -1.045 1 <0.036
MAD2L2 ENSG00000116670 Mitotic spindle assembly checkpoint protein MAD2B -1.0315 1 <0.036
AOF2 ENSG00000004487 Lysine-specific histone demethylase 1 -1.018 1 <0.036
ATAD3B ENSG00000160072 ATPase family AAA -1.0031 1 <0.036
  1. The p-values are computed for the weight value with the permutation test and adjusted with the Benjamini-Hochberg criteria.
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