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Table 1 Top genes with highest FC change between the average gene expression values between the gained and normal and lost and normal samples

From: Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells

HGNC

Gene

Gene description

Logarithmic fold change

Number

Adjusted p-value

GSTT1

ENSG00000184674

Glutathione S-transferase theta-1

1.8701

1

<0.0139

KCNMA1

ENSG00000156113

Calcium-activated potassium channel

1.7972

1

<0.0139

RNFT1

ENSG00000189050

RING finger and transmembrane

1.0443

1

<0.0139

APPBP2

ENSG00000062725

Amyloid protein-binding protein

0.9715

1

<0.0139

SMCHD1

ENSG00000101596

Structural maintenance of chromosomes exible hinge domain-containing protein 1

0.85418

1

<0.0139

NDC80

ENSG00000080986

Kinetochore protein NDC80 homolog

0.80433

1

<0.0139

HEATR6

ENSG00000068097

HEAT repeat-containing protein

0.77267

1

<0.0139

HLA-DRB5

ENSG00000198502

HLA class II histocompatibility antigen, DRB5 beta chain precursor

0.72371

5

<0.0139

METTL4

ENSG00000101574

Methyltransferase-like protein

0.70292

1

<0.0139

PPM1D

ENSG00000170836

Protein phosphatase 1D

0.6493

1

<0.0139

PDPN

ENSG00000162493

Podoplanin precursor (Glycoprotein 36)

-2.9885

1

<0.036

ALPL

ENSG00000162551

Alkaline phosphatase, tissue nonspecific isozyme precursor

-2.16

1

<0.036

NPPB

ENSG00000120937

Natriuretic peptides B precursor

-1.6065

1

<0.036

RCAN3

ENSG00000117602

Calcipressin-3 (Regulator of calcineurin 3)

-1.2506

1

<0.036

DFFA

ENSG00000160049

DNA fragmentation factor subunit alpha

-1.1259

1

<0.036

TPRG1L

ENSG00000158109

Tumor protein p63-regulated gene 1-like protein

-1.1232

1

<0.036

CDA

ENSG00000158825

Cytidine deaminase

-1.0503

1

<0.036

DDI2

ENSG00000197312

Protein DDI1 homolog 2

-1.045

1

<0.036

MAD2L2

ENSG00000116670

Mitotic spindle assembly checkpoint protein MAD2B

-1.0315

1

<0.036

AOF2

ENSG00000004487

Lysine-specific histone demethylase 1

-1.018

1

<0.036

ATAD3B

ENSG00000160072

ATPase family AAA

-1.0031

1

<0.036

  1. The p-values are computed for the weight value with the permutation test and adjusted with the Benjamini-Hochberg criteria.