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Table 1 Adaptive permutation recommendations

From: An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use

 

c

0.1

0.2

m

α p

b

r

b

r

1

0.05

1,900

115

475

34

5

0.01

9,900

120

2,475

36

50

1e-3

99,900

121

24,975

36

500

1e-4

999,900

121

249,975

36

1,000

5e-5

1,999,900

121

499,975

36

10,000

5e-6

19,999,900

121

4,999,975

36

100,000

5e-7

199,999,900

121

49,999,975

36

1,000,000

5e-8

1,999,999,900

121

499,999,975

36

  1. Recommendation of the number of permutations (b) and cut-off value (r) varying the number of SNPs (m), PWER (α p ) and precision level (c), with a fixed EWER (α e = 0.05).