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Figure 2 | BioData Mining

Figure 2

From: Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

Figure 2

Mitochondrial SNPs significantly associated with total cholesterol and type 2 diabetes. Regression analyses were performed to identify mtSNPs associated with: (A) total cholesterol and (B) type 2 diabetes (T2D). SNPs reaching the significance threshold of pā€‰<ā€‰0.05 were plotted using Synthesis-View. The -log10 p-values and effect sizes (beta coefficients for total cholesterol and odds ratios for T2D) are shown, plotted in order of base pair position. The dashed line for the beta coefficient values represents no effect on total cholesterol for a given SNP.

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