Table 6 11-factor and DPPS encoding for HLA-DPA1*0103/DPB1*0201
11-factor encoding | ||||||||
|---|---|---|---|---|---|---|---|---|
I C 50 cutoff | 100 | 300 | 500 | 1000 | 5000 | 10000 | 15000 | |
Sn Avg (%) | 96.15 | 95.83 | 94.14 | 90.24 | 76.29 | 68.91 | 71.09 | |
SR (ℓ 1) | Sp Avg (%) | 0.00 | 0.00 | 18.25 | 29.22 | 70.38 | 75.52 | 75.39 |
Acc Avg (%) | 86.21 | 79.31 | 77.28 | 71.29 | 73.31 | 72.64 | 73.61 | |
Sn Avg (%) | 96.19 | 96.32 | 95.20 | 93.44 | 89.10 | 83.78 | 72.69 | |
SVM | Sp Avg (%) | 16.67 | 21.00 | 22.14 | 24.57 | 58.29 | 72.09 | 81.24 |
Acc Avg (%) | 88.02 | 82.83 | 78.72 | 72.21 | 73.59 | 77.06 | 77.69 | |
DPPS encoding | ||||||||
Sn Avg (%) | 93.93 | 92.22 | 87.37 | 83.29 | 70.67 | 66.28 | 67.76 | |
SR (ℓ 1) | Sp Avg (%) | 18.33 | 11.00 | 26.67 | 51.00 | 75.86 | 80.78 | 85.85 |
Acc Avg (%) | 85.82 | 77.69 | 73.64 | 73.30 | 73.31 | 74.67 | 78.44 | |
Sn Avg (%) | 58.33 | 46.55 | 43.66 | 44.52 | 49.10 | 55.00 | 57.82 | |
SVM | Sp Avg (%) | 77.50 | 94.67 | 94.29 | 93.33 | 88.67 | 87.09 | 87.42 |
Acc Avg (%) | 60.42 | 55.14 | 55.08 | 59.72 | 68.99 | 73.62 | 75.33 | |