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Table 2 Frequency of cardiometabolic GxE and GWAS SNPs under positive selection

From: CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits

Dataset, all cardiometabolic traits

# LD blocks

# with Fst or iHS (%)

p

# with Fst (%)

p

# with iHS (%)

P

nonGxE GWAS

549

88 (16.0)

0.61

21 (3.8)

0.66

70 (12.8)

0.44

GxE

178

30 (16.9)

 

8 (4.5)

 

22 (12.4)

 
  1. p-value based on two-sample z-test.
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ISSN: 1756-0381