Figure 4
From: Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development
Basic Overview of Biofilter. Annotation: Biofilter allows researchers to annotate a list of loci with information from LOKI. For example, if a list of chromosome and base pair locations are provided, the researcher might want annotation with the list of current SNP identifiers for those loci, as well as what gene the SNP might be located within. Filtering: Biofilter allows a researcher to filter an input list (such as a list of SNPs) by another list (a list of genes), and then Biofilter will provide a list of those SNPs that only fall within the list of genes. Modeling starts with an input list of loci or regions that are then linked to gene regions in LOKI, those genes are then linked out to sources and groups. As a final step pairwise interaction models with implication indices are generated.