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Table 2 Over-represented drug and disease terms (P-value < 0.05)

From: Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining

A

 

   Term

Number of genes

   insulin

358

   dexamethasone

195

   nitric oxide

193

   estrogen

169

   adenosine

151

   estradiol

145

   rosiglitazone

125

   actinomycin

124

   actinomycin d

121

   glucagon

120

   thrombin

108

   progesterone

97

   trypsin

86

   nicotinamide

85

   metformin

84

   pioglitazone

82

B

 

  Term

Number of genes

  insulin resistance

381

  obesity

263

  inflammation

219

  diabetes mellitus

190

  cardiovascular disease

181

  Diabetes mellitus,type 2

173

  Oxygen deficiency

164

  fibrosis

138

  hyperinsulinemia

137

  Cancer of breast

131

  Adiposity

130

  cancer

128

  starvation

120

  1. The top scoring drug terms in the IR network from the CoPub database (A). Top scoring disease terms from the CoPub database in the IR network (B).