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Table 4 Percentage of reads aligned in S1 and S2 data sets by four aligners under different settings

From: How do alignment programs perform on sequencing data with varying qualities and from repetitive regions?

 

S1

S2

w/o trim

w/trim

w/o trim

w/trim

7,406,247

7,006,805

5,398,566

5,193,655

Randomly report one alignment per read

SOAP2

75.96%

91.45%

42.12%

76.81%

Bowtie

75.71%

91.36%

41.83%

76.67%

BWA

76.12%

91.80%

41.94%

76.88%

Novoalign

73.64%

91.60%

34.50%

76.94%

Suppress reads w/ multiple alignments

SOAP2

71.85%

85.90%

39.75%

71.31%

 

Bowtie

68.82%

81.90%

38.89%

68.63%

 

BWA

74.40%

84.07%

39.12%

69.75%

 

Novoalign

69.67%

86.09%

32.63%

71.63%