|
Network name
|
Ref
|
Type
|
Screen
|
Nodes
|
Edges
|
D
|
MND
|
MNDSD
|
MCC
|
|---|
|
Ito-Core
|
[42]
|
PI
|
PPI
|
426
|
568
|
0.006
|
2.667
|
3.919
|
0.093
|
|
VonMering
|
[49]
|
PI
|
PPI
|
573
|
2097
|
0.013
|
7.319
|
9.017
|
0.450
|
|
Schwikowski
|
[50]
|
PI
|
PPI
|
1297
|
1862
|
0.002
|
2.871
|
3.109
|
0.125
|
|
Y2H-CCSB
|
[43]
|
PI
|
PPI
|
964
|
1598
|
0.003
|
3.315
|
5.456
|
0.095
|
|
Y2H-Union
|
[43]
|
PI
|
PPI
|
1647
|
2682
|
0.002
|
3.257
|
5.334
|
0.086
|
|
AP/MS-Combined
|
[45]
|
PI
|
CCA
|
1004
|
8319
|
0.017
|
16.57
|
18.63
|
0.648
|
|
LC-Multiple
|
[48]
|
MT
|
LCI
|
1213
|
2621
|
0.004
|
4.322
|
4.533
|
0.337
|
|
Secretory-Map
|
[53]
|
GI
|
E-MAP
|
409
|
4175
|
0.050
|
20.42
|
23.82
|
0.251
|
|
Chromosome-Map
|
[54]
|
GI
|
E-MAP
|
735
|
17,185
|
0.064
|
46.76
|
43.61
|
0.233
|
|
Costanzo
|
[55]
|
GI
|
SGA
|
4319
|
74,984
|
0.007
|
29.96
|
41.86
|
0.062
|
|
Costanzo-Stringent
|
[55]
|
GI
|
SGA
|
3811
|
35,924
|
0.004
|
16.07
|
22.92
|
0.046
|
- Network types: PI, physical interactions; GI, genetic interactions; MT, mixed type. Screening methods: PPI, protein-protein interaction screen; CCA, protein co-complex association mapping; LCI, literate-curated interactions; E-MAP, epistatic miniarray profiling; SGA, synthetic genetic array mapping. Topological parameters: D, density; MND, mean node degree; MNDSD, standard deviation of MND; MCC, mean clustering coefficient of the network. Costanzo-Stringent sub-network was constructed using the interaction score cut-offs ε < -0.17 or ε > 0.21. In each network, we extracted the largest connected component to be used in the evaluations.
