Yeast sporulation case study. We depict query results from a Yeast sporulation data set. In the first query (a), we have 150 genes with early over expression pattern. This query is made more specific by creating a new timebox (b). Now, it returns genes that have a sustained over-expression pattern. By applying a move operation on the second timebox, we query for genes with a over-expression followed by expression decrease (c). We can look for further patterns by deleting the second timebox and move the first timebox down to obtain genes with under-expression patterns(d).