Table 1 Results of data mining on RA and CHD in PubMed and SinoMed with Chinese herbs Angelica and Salvia

Angelica

Inflammation

Apoptosis

Caspase 3, Caspases, bcl-2-Associated × Protein, Proto-Oncogene Proteins c-bcl-2, Transforming Growth Factor beta1, CD40 Ligand, Tumor Necrosis Factor-alpha, Tumor Suppressor Protein p53, Vascular Endothelial Growth Factor A

Leukocytes

Cyclooxygenase 1, Phospholipases A, Prostaglandin-Endoperoxide Synthases

Monocytes

Interleukin-8

Cytokines

Fibroblast Growth Factor 2, Intercellular Adhesion Molecule-1, Interleukin-2, Interleukin-6, NF-kappa B, Toll-Like Receptor 4, Transforming Growth Factor beta, Transforming Growth Factor beta1

Macrophages

Nitric Oxide Synthase Type II, Cyclooxygenase 2, Interleukin-2, NF-kappa B, Nitric Oxide Syn-thase, Tumor Necrosis Factor-alpha, Interleukin- 6, Cyclooxygenase 1, Interleukin-1, Prostaglandin- Endoperoxide Synthases

Salvia

Inflammation

Apoptosis

Caspase 3, Caspases, Proto-Oncogene Proteins c-bcl-2, bcl-2-Associated × Protein, Tumor Suppressor Protein p53, L-Lactate Dehydrogenase, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins, Tumor Necrosis Factor-alpha, Cyclooxygenase 2, Intercellular Adhesion Molecule-1, Interleukin-2, Interleukin-6, Interleukin-8, Platelet-Derived Growth Factor, Vascular Endothelial Growth Factor A

Leukocytes

Intercellular Adhesion Molecule-1, Tumor Necrosis Factor-alpha

Monocytes

Proto-Oncogene Proteins, Transforming Growth Factor beta1, Tumor Necrosis Factor-alpha

Cytokines

Alanine Transaminase, Tumor Necrosis Factor- alpha, Interleukin-6, Interleukin-8, Nitric Oxide Synthase Type II, Platelet-Derived Growth Factor, Prostaglandin- Endoperoxide Synthases, Transforming Growth Factor beta1

Macrophages

Nitric Oxide Synthase Type II, Tumor Necro-sis Factor-alpha, Cyclooxygenase 2, NF-kappa B, Interleukin-1, Interleukin-6, Nitric Oxide Synthase, Transforming Growth Factor beta1, Caspases, Chemokine CCL2, E-Selectin, Intercellular Adhesion Molecule-1, Matrix Metalloproteinase 9