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Table 3 Power Results for Purely Epistatic Simulated Models, n = 500

From: Grammatical evolution decision trees for detecting gene-gene interactions

Model Number

Heritability (%)

Minor Allele Frequency

Genetic Model

Power(%)

Power (Lib %)

    

GEDT

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C4.5

GEDT

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C4.5

31

1

0.25

XOR

37

1

0

67

4

0

32

1

0.5

XOR

45

2

0

79

3

0

33

2.5

0.25

XOR

68

1

0

82

4

0

34

2.5

0.5

XOR

75

0

0

93

6

0

35

5

0.25

XOR

83

0

0

98

7

0

36

5

0.5

XOR

90

1

0

99

8

0

37

7.5

0.25

XOR

95

0

0

93

2

0

38

7.5

0.5

XOR

95

4

0

99

7

0

39

10

0.25

XOR

96

3

0

100

11

0

40

10

0.5

XOR

95

0

0

100

10

0

  1. Summary characteristics for the models simulated are listed, including the minor allele frequency simulated, the heritability of the simulated model, and the genetic model used. Complete penetrance functions are available from the authors upon request.