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Figure 2 | BioData Mining

Figure 2

From: Transcriptome bioinformatic analysis identifies potential therapeutic mechanism of pentylenetetrazole in down syndrome

Figure 2

MAP kinase pathway showing counteracting commonality genes. Of the 419 DS upregulated genes, 9 mapped on to the pathway. Of the 41 counteracting commonality genes, i.e., genes common between PTZ downregulated and DS upregulated sets, 3 figured in the pathway map (BRAF, PAK1 and PRKCA; represented by the three orange color boxes). Note significant enrichment of MAP kinase pathway in counteracting commonality genes (p = 0.041).

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