Figure 1From: Transcriptome bioinformatic analysis identifies potential therapeutic mechanism of pentylenetetrazole in down syndrome Venn diagram showing overlaps among PTZ and DS genes. Of the 716 total up- and down-regulated genes in DS, 56 are common to the PTZ downregulated set. Of the 419 upregulated DS genes, 41 are common to the PTZ set. Of the 301 downregulated DS genes, 16 are common to the PTZ set. Note significant enrichment in PTZ and DS total versus PTZ and DS upregulated (p = 0.011) and depletion in PTZ and DS total versus PTZ and DS downregulated (p = 0.008).Back to article page