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Table 5 Significant transcriptional factors identified by the two-tailed non-parametric

From: Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Motif Occurrence Number p-value q-value Transcription Factors
NKTSSCGC 161 4.28E-12 7.49E-10 E2F1
RACCACGTGCTC 575 3.92E-08 3.43E-06 MYC/MAX
ARATKGAST 15 1.97E-06 0.000115 FOXM1
RGCAGSTG 15 4.79E-06 0.00021 MYOGENIN
VTGAACTTTGMMB 1217 4.24E-05 0.00149 HNF4ALPHA
AGATADMAGGGA 19 0.000158 0.00462 GATA4
ATGCCCATATATGGWNNT 111 0.000203 0.00507 SRF
TWSGCGCGAAAAYKR 10 0.000247 0.00514 E2F
TRRCCAATSRN 159 0.000264 0.00514 NFY
NNCCACGTGNNN 15 0.000495 0.00867 NMYC
CTCTAAAAATAACYCY 14 0.000618 0.00984 MEF2
GGTACAANNTGTYCTK 55 7.00E-04 0.0102 GRE
NBTGGGTGGTCN 15 0.00191 0.023 GLI
RRCAGGTGNCV 27 0.00197 0.023 E12
ACAAGATAA 7 0.00269 0.0288 EVI1
  1. Mann-Whitney rank sum tests from Day 1 to Day 2
  2. Significant transcriptional factors identified by the two-tailed non-parametric Mann-Whitney rank sum tests
  3. from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number genes containing that that transcriptional factor binding sites in the promoter regions. The p-value column illustrates the two-tailed Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The transcriptional factor column lists the name of the transcriptional factor which is known to bind to that motif. The total number of Refseq genes with raw expression levels at least 100 in either Day 1 or Day 2 is 7066.