Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Table 4 Tested novel motifs with mutagenesis

Motif	Occurrence number	p-value	Gene symbol	Fold change Ratio	Gene description	Known nearby Transcriptional factor binding sites
gcggaggc	1238	2.57E-06	pck2	0.2	Phosphoenol-pyruvate carboxykinase 2 (mitochondrial)	Oct-1, TFIIA
cgacccgt	95	3.60E-06	myog	5.2	myogenin	SREBP-1, MEF2, MEF3

Novel motifs tested with mutagenesis and their surrounding known transcriptional factor binding sites.

ISSN: 1756-0381