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Table 2 Significant transcriptional factors in down-regulated genes from Day 1 to Day 2

From: Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Motif Occurrence Number p-value q-value Transcription Factors
NKTSSCGC 116 4.47E-11 3.97E-09 E2F1
RACCACGTGCTC 351 2.31E-07 1.03E-05 MYC/MAX
GGGGCGGGGT 253 2.64E-06 7.82E-05 SP1
ARATKGAST 14 6.73E-06 0.000149 FOXM1
TRRCCAATSRN 95 1.56E-05 0.000278 NFY
NNCCACGTGNNN 12 0.000292 0.00415 NMYC
GGACATGCCCGGGCATGTCY 205 0.000327 0.00415 P53
TGACGTYA 65 0.000496 0.00551 CREBP1/CJUN
NBTGGGTGGTCN 12 0.00142 0.014 GLI
NNNNNCCATNTWNNNWN 64 0.00248 0.02 YY1
GCHCDAMCCAG 5 0.00916 0.0592 CP2
TGCTGAGTCAY 5 0.00945 0.0592 NFE2
TCATGTGN 9 0.0124 0.0675 TFE
TGACGTMA 90 0.0136 0.0675 CREB
TWSGCGCGAAAAYKR 10 0.0141 0.0675 E2F
  1. Significant transcriptional factors in down-regulated genes from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number of genes containing that motif in the promoter regions. The p-value column illustrates the Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The last column lists the name of the transcription factor. The total number of down-regulated Refseq genes with raw expression levels at least 100 in Day 1 is 3728.