|
Motif
|
Occurrence Number
|
p-value
|
q-value
|
Transcription Factors
|
|---|
|
NKTSSCGC
|
116
|
4.47E-11
|
3.97E-09
|
E2F1
|
|
RACCACGTGCTC
|
351
|
2.31E-07
|
1.03E-05
|
MYC/MAX
|
|
GGGGCGGGGT
|
253
|
2.64E-06
|
7.82E-05
|
SP1
|
|
ARATKGAST
|
14
|
6.73E-06
|
0.000149
|
FOXM1
|
|
TRRCCAATSRN
|
95
|
1.56E-05
|
0.000278
|
NFY
|
|
NNCCACGTGNNN
|
12
|
0.000292
|
0.00415
|
NMYC
|
|
GGACATGCCCGGGCATGTCY
|
205
|
0.000327
|
0.00415
|
P53
|
|
TGACGTYA
|
65
|
0.000496
|
0.00551
|
CREBP1/CJUN
|
|
NBTGGGTGGTCN
|
12
|
0.00142
|
0.014
|
GLI
|
|
NNNNNCCATNTWNNNWN
|
64
|
0.00248
|
0.02
|
YY1
|
|
GCHCDAMCCAG
|
5
|
0.00916
|
0.0592
|
CP2
|
|
TGCTGAGTCAY
|
5
|
0.00945
|
0.0592
|
NFE2
|
|
TCATGTGN
|
9
|
0.0124
|
0.0675
|
TFE
|
|
TGACGTMA
|
90
|
0.0136
|
0.0675
|
CREB
|
|
TWSGCGCGAAAAYKR
|
10
|
0.0141
|
0.0675
|
E2F
|
- Significant transcriptional factors in down-regulated genes from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number of genes containing that motif in the promoter regions. The p-value column illustrates the Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The last column lists the name of the transcription factor. The total number of down-regulated Refseq genes with raw expression levels at least 100 in Day 1 is 3728.
