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Table 1 Significant transcriptional factors in up-regulated genes from Day 1 to Day 2

From: Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Motif Occurrence Number p-value q-value Transcription Factors
RRCAGGTGNCV 17 3.87E-05 0.00274 E12
SRACAGGTGKYG 23 0.000125 0.00399 MYOD
RSTGACTNMNW 65 0.000253 0.00399 AP1
GGTACAANNTGTYCTK 34 0.000282 0.00399 GRE
GGACATGCCCGGGCATGTCY 170 0.000306 0.00399 P53
GGGGCGGGGT 245 0.000338 0.00399 SP1
NNRYCACGTGRYNN 38 0.000422 0.00426 USF
CTCTAAAAATAACYCY 11 0.000485 0.00429 MEF2
ATGCCCATATATGGWNNT 67 0.000605 0.00475 SRF
GAAAAGYGAAASY 8 0.00178 0.0126 IRF2
AGATADMAGGGA 15 0.0029 0.018 GATA4
CKSNYTAAAAAWRMCY 4 0.00305 0.018 MMEF2
TGACGTYA 49 0.00389 0.0192 CREBP1/CJUN
RGCAGSTG 14 0.00398 0.0192 MYOGENIN
GGGRATTTCC 75 0.0041 0.0192 NFKAPPAB65
  1. Significant transcriptional factors in up-regulated genes from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number genes containing that that transcriptional factor binding sites in the promoter regions. The p-value column illustrates the Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The transcriptional factor column lists the name of the transcriptional factor which is known to bind to that motif. The total number of up-regulated Refseq genes with raw expression levels at least 100 in Day 2 is 3338.