Data Source
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Genotyping and Phenotyping
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Entrez Gene
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Current Availability of Data
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Limited
|
Available
|
Expense
|
High
|
Free (Taxpayer Subsidized)
|
Sensitivity
|
Low; limited number of markers tested
|
Low; much remains unknown about most genes
|
Positive Predictive Value
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Low; many false positives
|
High; curated information is backed by experimental data and peer review
|
Population Specific
|
Yes
|
Generally no, although population specific information may be included in some records
|
Specific Variants Identified
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Yes, although SNPs that tag haplotypes may not be disease causing variants
|
Generally no, although specific variants may be annotated. Separate genotyping is usually required for validated candidates
|
Multi-Gene Effects on Phenotype
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Limited
|
Yes
|
Complex Phenotypes
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Limited
|
Yes
|