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Figure 9 | BioData Mining

Figure 9

From: Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing

Figure 9

Fisher's linear discriminant discriminates between wild type and mutant phenotypes. 2-D scatter plots of wild type vs. EP+ (a) Wild type vs. bchs1 and (b) Wild type vs. bchs 58 (c) in Fisher's space spanned by axes ω12, ω13 and ω14. Note that the scatter plots in (b) and (c) show that the wild type differs from bchs1 and bchs58, the two loss of function alleles, in the same way (spanned by the same projection axes and having similar distributions), but that WT deviation from the EP+ (Bchs overexpression) profile is clearly distinct from those of bchs1 and bchs58 (different projection axes and distributions).

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