Table 5 Top important biomarkers identified through our algorithm
From: MOCAT: multi-omics integration with auxiliary classifiers enhanced autoencoder
Dataset | Omics | Top identified biomarkers |
|---|---|---|
ROSMAP | mRNA | NPNT, ANKRD30B, TCEA3, PRTN3, ZNF652-AS1, SAMD4A, SYTL1, AC131056.3, NRIP2 |
methy | C10orf99, RORC, CRMP1, TMEM59, SNRPA, NGEF, C1orf83, TMEM85, ATP6V1B1, KIAA1267, HYAL2 | |
miRNA | hsa-miR-375, hsa-miR-767-5p, hsa-miR-146b-5p, hsa-miR-651, hsa-miR-93, hsa-miR-1266, hsa-let-7i, hsa-miR-224, hsa-miR-129-5p, hsa-miR-132, hsa-miR-330-3p | |
BRCA | mRNA | ZIC4, SCN7A, HPDL, PPP1R14C, SFRP1, TRIM29, WDR67, DUSP7, FABP7, PI3, CAMKV , CCDC150, CDKN2A, COG2, FANCE, NR2E1, PHOSPHO2, C1orf112, C9orf100, CCDC99, FANCB, GSG2, LBR, NUBPL, SGOL2, YBX1 |
methy | COQ3, SOX21 | |
miRNA | hsa-mir-9-3, hsa-mir-374a, hsa-mir-92b | |
LGG | mRNA | LOC349196, TMEM179, BBC3, WDR53, ZNF77, ZSCAN16, GSTM3, LOC442308, LBX2, BPHL, APOL4, BTN2A2, DUSP10, GP9, HGF, IRGM, LOC222699, LYVE1, MSX2P1, TARSL2 |
methy | SIGLEC11, GDF3, TWSG1, OR6Q1 | |
miRNA | hsa-mir-1234, hsa-mir-142, hsa-mir-21, hsa-mir-3655, hsa-mir-618, hsa-mir-9-3 |