Table 2 Comparison with state-of-the-art methods on ROSMAP and BRCA datasets
From: MOCAT: multi-omics integration with auxiliary classifiers enhanced autoencoder
Method | ROSMAP (2 Categories) | BRCA (5 Categories) | ||||
|---|---|---|---|---|---|---|
ACC(%) | F1(%) | AUC(%) | ACC(%) | F1\(\_\)w(%) | F1\(\_\)m(%) | |
(95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | |
KNN | 65.7 (61.2-70.2) | 67.1 (61.6-72.6) | 70.9 (65.3-76.5) | 74.2 (71.2-77.2) | 73.0 (70.1-75.9) | 68.2 (65.1-71.3) |
SVM | 77.0 (74.0-80.0) | 77.8 (75.8-79.8) | 77.0 (73.8-80.2) | 72.9 (70.7-75.1) | 70.2 (68.3-72.1) | 64.0 (61.9-66.1) |
Lasso | 69.4 (64.8-74.0) | 73.0 (68.9-77.1) | 77.0 (72.7-81.3) | 73.2 (71.7-74.7) | 69.8 (67.9-71.7) | 64.2 (61.0-67.4) |
RF | 72.6 (69.0-76.2) | 73.4 (70.8-76.0) | 81.1 (78.7-83.5) | 75.4 (74.3-76.5) | 73.3 (72.1-74.5) | 64.9 (63.3-66.5) |
XGBoost | 76.0 (70.3-81.7) | 77.2 (71.6-82.8) | 83.7 (80.0-87.4) | 78.1 (77.1-79.1) | 76.4 (75.2-77.6) | 70.1 (68.0-72.2) |
NN | 75.5 (72.9-78.1) | 76.4 (73.8-79.0) | 82.7 (79.6-85.8) | 75.4 (71.9-78.9) | 74.0 (69.8-78.2) | 66.8 (61.0-72.6) |
GRridge | 76.0 (71.8-80.2) | 76.9 (73.3-80.5) | 84.1 (81.2-87.0) | 74.5 (72.5-76.5) | 72.6 (70.2-75.0) | 65.6 (62.5-68.7) |
BPLSDA | 74.2 (71.2-77.2) | 75.5 (72.6-78.4) | 83.0 (79.9-86.1) | 64.2 (63.1-65.3) | 53.4 (51.7-55.1) | 36.9 (34.8-39.0) |
BSPLSDA | 75.3 (71.2-79.4) | 76.4 (72.1-80.7) | 83.8 (81.2-86.4) | 63.9 (62.9-64.9) | 52.2 (50.2-54.2) | 35.1 (32.4-37.8) |
CF | 78.4 (77.0-79.8) | 78.8 (78.2-79.4) | 88.0 (87.4-88.6) | 81.5 (80.5-82.5) | 81.5 (80.4-82.6) | 77.1 (76.0-78.2) |
GMU | 77.6 (74.5-80.7) | 78.4 (76.4-80.4) | 86.9 (84.9-88.9) | 80.0 (75.2-84.8) | 79.8 (72.3-86.7) | 74.6 (67.4-81.8) |
Mogonet | 81.5 (78.6-84.4) | 82.1 (79.4-84.8) | 87.4 (85.9-88.9) | 82.9 (80.7-85.1) | 82.5 (80.5-84.5) | 77.4 (75.3-79.5) |
Dynamics | 84.2 (83.6-84.8) | 84.6 (84.3-84.9) | 91.2 (90.9-91.5) | 87.7 (87.6-87.8) | 88.0 (87.8-88.2) | 84.5 (84.3-84.7) |
MOCAT(Ours) | 87.6 \(^*\) (86.7-88.5) | 87.5 \(^*\) (86.8-88.2) | 92.3 \(^*\) (91.2-93.4) | 88.5 \(^*\) (88.1-88.9) | 88.9 \(^*\) (88.5-89.3) | 86.2 \(^*\) (85.3-87.1) |