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Fig. 8 | BioData Mining

Fig. 8

From: Interaction models matter: an efficient, flexible computational framework for model-specific investigation of epistasis

Fig. 8

Representations of three-way epistasis in rats. A and B Bar graphs of occurrences of three-way epistatic events in GWAS QTLs under Cartesian (A, orange bars) and XOR (B, blue bars) models. C and D Interaction plots of Cartesian (C) XOR (D) three-way epistasis of GWAS QTLs across rat autosomes. Autosome numbers are depicted as roman numerals and increase clockwise. Orange bars represent counts of epistatic instances per locus. E Venn diagram of epistatic triplets for GWAS QTLs under Cartesian (left circle) model, the intersect between models (center) and under XOR (right circle) model. E Color gradient illustrates low (white) to high (blue) occurrences

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BioData Mining

ISSN: 1756-0381