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Fig. 2 | BioData Mining

Fig. 2

From: Interaction models matter: an efficient, flexible computational framework for model-specific investigation of epistasis

Fig. 2

Representations of epistasis in mice. A Interchromosomal (blue squares) vs. intrachromosomal (light purple squares) pairs under XOR model. B Number of pairs involving no (pink squares), one (green squares), or two (yellow squares) putative GWAS QTL under XOR model. C Non-QTL-associated (gray squares) and QTL-associated (dark purple squares) epistatic loci under XOR model. D Interaction plot of XOR epistasis across mouse autosomes. Autosome numbers are depicted as roman numerals and increase clockwise. Orange bars represent counts of epistatic instances per locus. E Venn diagram of epistatic pairs under Cartesian (left circle) model, the intersect between models (center), and under XOR (right circle) model. F Venn diagram of epistatic loci under Cartesian (left circle) model, the intersect between models (center), and under XOR (right circle) model. E and F Color gradient illustrates low (white) to high (blue) occurrences

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BioData Mining

ISSN: 1756-0381