Table 1 Effect of cardiovascular diseases on gut microbiota
Exposure | Outcome | Methods | Number of SNPs | OR (95% CI) | Beta (SE) | P-value | Pleiotropy | Heterogeneity | |
|---|---|---|---|---|---|---|---|---|---|
P-value | I2 (%) | P-value | |||||||
AF | Dorea | MR Egger | 96 | 1.067 (1.001–1.137) | 0.06 (0.03) | 0.05 | 0.09 | 0 | 0.82 |
AF | Streptococcus | IVW | 96 | 0.964 (0.931–0.998) | -0.04 (0.02) | 0.04 | 0.3 | 2.9 | 0.4 |
IS | Alistipes | IVW | 4 | 0.930 (0.869–0.995) | -0.07 (0.03) | 0.04 | 0.79 | 0 | 0.64 |
IS | Eubacterium brachy group | IVW | 4 | 0.846 (0.733–0.977) | -0.17 (0.07) | 0.02 | 0.14 | 52.4 | 0.1 |
IS | Rikenellaceae RC9 gut group | IVW | 4 | 0.855 (0.731–0.999) | -0.16 (0.08) | 0.05 | 0.37 | 0 | 0.48 |