Disc. Rank | SNP 1 | SNP 2 | Locus 1 | Locus 2 | Beta | LRT p | Rep. Beta | Rep. LRT p | Rep. Cohorta | |
---|---|---|---|---|---|---|---|---|---|---|
HDL | 1 | rs12720918 | rs4783961 | CETP | CETP | −0.06 | 9.5 × 10−20 | −0.07 | 3.0 × 10−12 | P,W,L |
2 | rs12720918 | rs158477 | CETP | CETP | −0.06 | 6.3 × 10−16 | −0.07 | 2.9 × 10−10 | P,W,L | |
3 | rs1864163 | rs4783961 | CETP | CETP | −0.06 | 4.5 × 10−15 | −0.05 | 7.1 × 10−7 | P,W,B | |
5 | rs1864163 | rs158477 | CETP | CETP | −0.06 | 1.3 × 10−12 | −0.05 | 2.3 × 10−8 | P | |
6 | rs12708967 | rs820299 | CETP | CETP | 0.06 | 1.0 × 10−11 | 0.06 | 1.6 × 10−6 | P,W,L | |
7 | rs1864163 | rs4784744 | CETP | CETP | 0.05 | 2.6 × 10−11 | 0.06 | 5.2 × 10−11 | P,W | |
8 | rs1800775 | rs4783961 | CETP | CETP | 0.04 | 6.3 × 10−11 | −0.08 | 2.4 × 10−7 | B | |
9 | rs12708967 | rs158477 | CETP | CETP | −0.05 | 2.5 × 10−10 | −0.06 | 1.1 × 10−6 | P,W,L | |
10 | rs9939224 | rs4783961 | CETP | CETP | −0.05 | 2.5 × 10−10 | −0.04 | 2.4 × 10−7 | W,B | |
12 | rs1800775 | rs158477 | CETP | CETP | 0.04 | 1.8 × 10−8 | 0.07 | 2.5 × 10−6 | B | |
13 | rs9939224 | rs478474 | CETP | CETP | 0.04 | 5.4 × 10−7 | 0.07 | 2.4 × 10−10 | P | |
17 | rs1800775 | rs4784744 | CETP | CETP | −0.03 | 1.8 × 10−6 | −0.05 | 9.7 × 10−7 | W | |
18 | rs9939224 | rs12447924 | CETP | CETP | 0.05 | 1.8 × 10−6 | 0.06 | 5.3 × 10−7 | P | |
38 | rs7013777 | rs9644636 | LPL | LPL | −0.03 | 8.0 × 10−5 | −0.04 | 7.5 × 10−6 | W | |
50 | rs820299 | rs8056954 | CETP | SLC12A3 | 0.03 | 1.8 × 10−4 | 0.06 | 1.5 × 10−5 | W | |
66 | rs12708967 | rs4784744 | CETP | CETP | 0.03 | 3.0 × 10−4 | 0.05 | 2.4 × 10−5 | P | |
133 | rs6586891 | rs285 | LPL | LPL | −0.02 | 7.9 × 10−4 | −0.04 | 2.9 × 10−5 | P | |
LDL | 7 | rs1531517 | rs519113 | BCL3 | PVRL2 | −0.16 | 7.9 × 10−6 | −0.2 | 5.2 × 10−6 | P,B |
70 | rs4803766 | rs157580 | PVRL2 | TOMM40 | −0.06 | 3.4 × 10−4 | −0.11 | 4.8 × 10−7 | P,B | |
TC | 33 | rs11216129 | rs10750097 | BUD13 | APOA5 | −0.12 | 1.3 × 10−4 | −0.22 | 1.4 × 10−5 | W |
TG | 1 | rs4938303 | rs180327 | BUD13 | BUD13 | 0.09 | 1.2 × 10−21 | 0.08 | 9.5 × 10−7 | P,W |
2 | rs2075295 | rs6589568 | BUD13 | APOA4 | −0.10 | 4.4 × 10−19 | −0.15 | 3.5 × 10−15 | P,W | |
3 | rs180327 | rs10750097 | BUD13 | APOA5 | 0.08 | 3.1 × 10−14 | 0.31 | 6.8 × 10−9 | W,B | |
4 | rs180327 | rs2075295 | BUD13 | BUD13 | 0.07 | 8.9 × 10−13 | 0.07 | 1.5 × 10−5 | P | |
5 | rs180327 | rs6589568 | BUD13 | APOA4 | 0.07 | 2.7 × 10−10 | 0.08 | 5.6 × 10−6 | W | |
6 | rs11216129 | rs10750097 | BUD13 | APOA5 | −0.12 | 2.1 × 10−9 | −0.12 | 2.6 × 10−7 | W,P | |
13 | rs180327 | rs618923 | BUD13 | ZPR1 | −0.08 | 3.7 × 10−7 | −0.08 | 1.0 × 10−5 | W | |
15 | rs2075295 | rs1263173 | BUD13 | APOA4 | −0.08 | 2.1 × 10−7 | −0.08 | 3.5 × 10−6 | W | |
19 | rs486394 | rs4938303 | BUD13 | BUD13 | 0.07 | 2.1 × 10−6 | 0.07 | 2.9 × 10−5 | P | |
49 | rs2075295 | rs10047459 | BUD13 | APOA1 | −0.11 | 2.1 × 10−5 | −0.11 | 6.9 × 10−8 | W | |
153 | rs2075295 | rs10750097 | BUD13 | APOA5 | −0.09 | 2.1 × 10−4 | −0.09 | 2.9 × 10−6 | W |