Identification of SNPs associated with variola virus virulence

Table 1 Summary of models evaluated by MDR for predicting smallpox outbreak CFRs using VARV SNPs

	All isolates								Primary cladel I* isolates only
No. SNPs consi-dered	Unadjusted models				Adjusted model				Unadjusted models
	SNPs in best model	CVC	Testing balance	P	SNPs in best model	CVC	Testing balance	P	SNPs in best model	CVC	Testing balance	P
1	18083	3/5	0.8268	0.018	127469	5/5	0.7365	0.020	183426	4/5	0.8333	0.010
2	Group 1,127469	3/5	0.8562	0.003	Group 1, 127469	4/5	0.8227	<0.001	Group 1, 127469	4/5	0.9042	<0.001
3	75336, 127469, 183083	3/5	0.8268	0.018	127469, Group 2, 42293	3/5	0.8067	<0.001	Group 1, Group 2, 127469	3/5	0.9042	<0.001

ISSN: 1756-0381