Figure 6
From: Using random walks to identify cancer-associated modules in expression data
CCA module 144. Module 144 shows interactions among cell cycle regulatory genes and FOXM1 oncogene. WEE1, CDC25C, YWHAE and BRSK1 are also involved in cell cycle control and interact closely with cancer-associated genes, but are not themselves well-described as cancer genes. Also of note, WEE1 and CDC25C are known to play an antagonistic role in regulating the cell cycle. Red nodes designate cancer-associated genes based on descriptions in OMIM. Node sizes correspond to the absolute values of the fold change of differentially regulated genes (up- or down-regulated). Blue edges are derived from HPRD, green from KEGG, and orange from both databases.